MacMillan's 10-Step Neurodiverse Family Systems Approach:

A Comprehensive Framework

to support neurodivergents and their families throughout adulthood.

R.E.A.L. Neurodiverse Programs For Professionals

WHAT ARE THE R.E.A.L. PROGRAMS?

Autism and other forms of neurodivergence shape how adults engage in social relationships—especially in families and intimate partnerships, where emotional demands run high and communication styles often differ.

Developed by Anne MacMillan, MLA, the R.E.A.L. Neurodiverse programs offer a clear, research-informed path forward. Built around a structured 10-step approach, these programs translate neuroscience, developmental psychology, and clinical insight into practical tools for real-life change. Adults gain access to targeted education, specialized assessments, and concrete strategies for building skills, making decisions, and strengthening relationships.

As awareness of adult neurodivergence expands, so does the demand for services that meet the moment—with depth, precision, and respect for every individual’s way of being.

WHY SHOULD YOUR PRACTICE USE THE R.E.A.L. PROGRAMS?

Neurodiverse families are commonly made up of autistic, attention neurodivergent (ADHD), and other neurodivergent family members. The different brains' different ways of perceiving and navigating the social world affect family social interactions, eliciting difficulties and distress that commonly lead to trauma and isolation.

In the mid-20th century, before neurodivergence in aNeurodiverse families often include autistic, attention neurodivergent (ADHD), and other neurodivergent members. Differences in how each brain processes social and emotional information shape everyday interactions—frequently leading to misunderstanding, relational strain, and social isolation.

In the mid-20th century, long before adult neurodivergence was recognized, psychology framed mental and relational challenges as evidence of disorder. Many neurodivergent individuals—unaware of their neurological differences—were mischaracterized as broken or dysfunctional. These labels disempowered them, and treatments that failed to account for brain-based variation often offered little meaningful support.

In the early 21st century, autism’s prevalence in children came into focus. Only now are we beginning to recognize the widespread presence of neurodivergence in adults. These adults are not disordered. They do not need to be “fixed.” They need access to insight, language, and tools that respect their neurology—so they can build skills, reduce suffering, and strengthen their relationships.

The R.E.A.L. Neurodiverse programs offer that path forward.dults was understood or recognized, psychologists began defining mental disorders that required treatment. Many neurodivergents, completely unaware that their brains were different, were unjustly labeled as "disordered" or "broken." These labels disempowered neurodivergents and treatments that didn't recognize brain differences offered little relevant support.

The high prevalence of autism in children was discovered in the early years of the 21st century. Today, we are finally recognizing multiple neurodivergencies in adulthood. These adults aren't "broken." They don't need "treatment" for "disorders." They need to understand the nuances of brain differences and have access to resources that will help them leverage their strengths and build skills to address their challenges.

The R.E.A.L. Neurodiverse programs offer solutions: solutions that work.

R.E.A.L. Neurodiverse

Resources & Education Across the Lifespan

Anne MacMillan, MLA

Author of the 10-Step Neurodiverse Family Systems Approach, Speaker, Researcher, Consultant, Coach, Educator and Expert Witness

WHO ARE THE R.E.A.L. PROGRAMS FOR?

Our comprehensive 10-step method is designed for use by psychologists, therapists, social workers, counselors, teachers, coaches, consultants, clergy, domestic violence workers, victim advocates and more.

The R.E.A.L. Neurodiverse Family Systems Approach is a comprehensive 10-step method for coaches, consultants, teachers, therapists, psychologists, social workers, mediators, domestic violence workers, victim advocates, spiritual leaders, and more.

The approach is designed to support professional growth through both structured education and direct relational experience. To access the full programs, at least one provider per office must complete our NFS-E Credential and become a Neurodiverse Family Systems – Educator. This ensures that each office has a designated provider who understands the framework and can guide implementation with fidelity.

While only one team member is required to complete the full credentialing process, all other providers receive meaningful and accessible support to ensure high-quality care across the team. Every provider begins with a clear, neurologically informed orientation that introduces the program’s foundational concepts, implementation principles, and ethical guidelines. From there, learning continues through guided use of the program materials with clients. As clients move through the 10-step structure, providers gain access to corresponding provider resources—learning in real time how to support neurologically diverse adults with clarity and care.

This approach reflects a core truth of neurodiverse relational systems work: while structured training is essential, deep understanding develops through direct experience. The program honors this by allowing providers to grow alongside their clients. Even those who are new to neurodiverse systems will find that the materials are intuitive, grounded, and developmentally attuned—inviting providers to apply their own wisdom while building confidence in a new and important domain.

WHAT MAKES R.E.A.L. DIFFERENT?

Traditional interventions are grounded in the assumption that relationship conflict can be resolved through shared dialogue and emotional processing. But in neurodiverse families and intimate life partnerships, these methods often overlook the root cause of distress: neurological mismatch.

The R.E.A.L. Neurodiverse model introduces a fundamental paradigm shift. Instead of beginning with group sessions, we start with the individual—recognizing that perception, empathy, expression, and regulation differ profoundly across neurotypes. Our structured 10-step program replaces generalized talk therapy with neurotype-specific education, tools, and developmental supports.

This shift moves providers away from pathologizing behavior and toward honoring difference. It reframes family and intimate partnership conflict not as dysfunction, but as the result of unmet neurological needs—and offers a clear, compassionate pathway for lasting change, even when only one partner or family member is ready to begin.

HOW DO THE R.E.A.L. PROGRAMS WORK?

The R.E.A.L. Neurodiverse Family Systems Approach guides adults—and the professionals who support them—through a structured but flexible 10-step process designed to build insight, reduce distress, and support sustainable relational growth. Clients receive materials tailored to their neurology (autistic or non-autistic), while providers use parallel resources that align with the client’s processing style.

Each of the 10 steps addresses a core dimension of neurodiverse relational life—such as empathy differences, neurological mismatch, relational role entrenchment, boundary development, problem solving, and cycles of trauma. Steps are sequential but adaptable, allowing providers to meet clients where they are without sacrificing developmental integrity.

Clients move through video-based educational content, guided assessments, structured reflection prompts, and integrative exercises that help them make sense of their experiences through a neurologically attuned lens. Providers receive step-specific guides that support interpretation, discussion, and skill-building, ensuring that support remains aligned with the client’s neurotype and developmental readiness.

Unlike many traditional models that prioritize behavior change or surface-level communication strategies, the R.E.A.L. Approach integrates neurological, emotional, somatic, and systemic layers of experience.

Tools range from conceptual mappings and guided journaling to artwork-based exercises and somatic strategies—supporting a wide range of processing styles and learning needs.

Because each client engages individually, the program remains effective whether or not other family members or partners are involved. When multiple participants are ready, shared theory and neurologically specific tools create a common language for growth without forcing consensus or conformity.

About Anne MacMillan:

I built my original Neurodiverse Family Systems Theory on my education, personal life experience, and the professional experience I gained in the private neurodiverse services practice I founded in 2017.

Today, my services extend to support other professionals who have come to the new realization that neurodiversity is at the heart of many of the relationship challenges their adult clients face. Professionals can use my practical 10-Step educational system, including quantitative assessments, integration practices, and support resources to help their clients comprehend their relationship challenges and find the happiness and peace they deserve.

I have a research-based master's in psychology from Harvard University and studied developmental psychology as an undergrad. I received the Director's Thesis Award at Harvard for my original research on Level 1 autism and intimate life partnerships — some of the first quantitative research on the subject in the world.

Altogether, I have over 50 years of personal life experience with neurodiverse family systems (I was born into a neurodiverse family), over 20 years of personal life experience with neurodiverse intimate life partnerships, and 8 years of professional experience working with individuals managing the challenges of neurodiverse family systems.

I self-identify as a high body empathetic neurodivergent and attention neurodivergent (ADHD). I am not autistic.

Anne MacMillan, MLA

Author of the R.E.A.L. 10-Step Neurodiverse Family Systems Approach, Speaker, Researcher, Consultant, Coach, Educator and Expert Witness

Recent Blog Posts

Anne MacMillan, MLA with the words "Understanding Empathy and Neurodiversity: Beyond the Mirror Neuron System Debate

How a Meta-Analysis Ended the "Broken Mirror Neuron Debate" on Autism and Empathy

August 06, 20244 min read

The debate around how the mirror neuron system affects empathy in autistic and non-autistic individuals has been a point of contention in neuroscience. The discussion often centers on whether differences in the mirror neuron system contribute to the different ways empathy is experienced by autistic and non-autistic individuals. A recent meta-analysis by researchers Chan and Han provides clarity, effectively ending the "Broken Mirror Neuron Debate."

The Meta-Analysis by Chan and Han

In 2020, researchers Chan and Han published a meta-analysis that brought together findings from numerous studies on the relationship between autism and the mirror neuron system. A meta-analysis is a comprehensive review that aggregates data from multiple studies, using statistical methods to identify patterns or draw conclusions that may not be apparent in individual studies.

The meta-analysis by Chan and Han analyzed studies with varying methodologies, subjects of different ages, and various stimuli used during experiments. They found that these factors contributed to inconsistent results in earlier studies. By standardizing the analysis, they concluded that the mirror neuron system does indeed function differently in autistic individuals compared to non-autistic individuals, but it is not "broken."

Different Does Not Mean 'Impaired' or 'Broken'

Chan and Han's meta-analysis described the mirror neuron system in autistic individuals as "impaired." This language reflects a medical model that often categorizes neurological differences as deficits, viewing minority neurological variations as abnormalities rather than natural variations with their own unique strengths. This perspective can overlook the evolutionary advantages and distinct contributions that diverse neurological profiles bring to human experience.

Using terms like "impaired" can be stigmatizing. By adopting language that respects this perspective, we can foster acceptance and appreciation of all forms of neurodiversity, emphasizing support rather than correction. Aligning thinking with natural evolutionary variations rather than focusing on "disorders" and "impairments" will also support researchers in asking better questions so they can find better answers.

The Role of Mirror Neurons

Mirror neurons are a type of brain cell that respond when we perform an action and when we observe someone else performing the same action. This mirroring mechanism is essential for understanding social interactions and empathy. Vittorio Gallese introduced the concept of embodied simulation, which suggests that mirror neurons allow individuals to internally simulate the actions and emotions of others, providing a basis for empathy.

Implications of the Meta-Analysis

The findings from Chan and Han’s meta-analysis show that differences in the mirror neuron system contribute to the diverse expressions of empathy among autistic and non-autistic individuals. In autistic individuals, these differences manifest as what is often called emotion-sharing empathy, where they deeply resonate with the emotions of others. In contrast, non-autistic individuals typically experience what Anne MacMillan terms body empathy, involving the physical mirroring of actions and emotions.

Autism is a spectrum, and the functioning of the mirror neuron system can vary significantly among autistic individuals. Some individuals, autistic or not, experience higher levels of embodied simulation, in which their mirror neuron systems engage more actively in simulating others' actions and emotions. This variation within the autism spectrum and among the wider population means that empathy experiences can differ greatly. Acknowledging and understanding this variability is essential for recognizing the unique ways in which autistics and non-autistics connect with and interpret the world around them.

Moving Forward

The resolution of the broken mirror neuron debate through Chan and Han's meta-analysis provides a clear acknowledgment that autistic and non-autistic mirror neuron systems function differently. This understanding can help inform more effective support and interventions for neurodiverse individuals and their non-autistic neurodivergent family members (including attention neurodivergents and high body empathetics) who may also have mirror neuron system differences in comparison to the general neurotypical population.

In conclusion, Chan and Han's meta-analysis effectively resolves the "broken mirror neuron debate," but the reliance on medical language that emphasizes impairments instead of differences may limit the scope of future research. This approach risks framing neurological differences as deficits rather than as natural variations within human evolution. By recognizing the diverse ways empathy is experienced, we can better appreciate the strengths and challenges faced by all individuals, autistic or not. This understanding fosters a more inclusive society that offers more comprehensive support and insights for all neurodivergents and all members of neurodiverse family systems.

Support for Clients

Neurodiverse Credentialing and Practice Support for Psychologists, Therapists, Social Workers, Clergy, and Domestic Violence workers is available here.

Autistic and non-autistic members of neurodiverse family systems can reach out for support here.


Resources for Further Exploration


Read Vittorio Gallesse's 2007 article entitled "Before and Below 'Theory of Mind': Embodied Simulation and the Neural Correlates of Social Cognition" published by The Royal Society, 362(1480), doi:10.1098/rstb.2006.2002.

Read Chan and Han's 2020 meta-analysis entitled "Differential Mirror Neuron System (MNS) Activation During Action Observation with and without Social-Emotional Components in Autism: A Meta-Analysis of Neuroimaging Studies" published in Molecular Autism, (11)72, doi:10.1186/s13229-020-00374-x.

Read Acharya and Shukla's 2012 paper entitled "Mirror Neurons: Enigma of the Metaphysical Modular Brain" published by the Journal of Natural Science and Biological Medicine, 3(2), pp. 118-124, doi:10.4103/0976-9668.101878.

Read Anne MacMillan's 2025 book entitled Neurodiverse Family Systems: Theory and Practice, available for pre-order.

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Anne MacMillan, MLA

Anne MacMillan, MLA is the founder of R.E.A.L. Neurodiverse 10-Step Family Systems Approach, designed to support Level 1 autistic adults and their neurodivergent and neurotypical family members as they come to understand what makes them different, work to improve their relationships, and take action to improve their lives. MacMillan has over 50 years of personal life experience with neurodiverse family systems, over 20 years of personal life experience in a neurodiverse intimate life partnership, and has been professionally supporting autistics and non-autistic adults in neurodiverse close family relationships since 2017. She has a master's in psychology from Harvard University where she did some of the world's first quantitative research on autism and intimate life partnerships. She self-identifies as a high body empathetic, or a non-autistic neurodivergent with a high level of body empathy.

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Anne MacMillan, MLA

Author of the R.E.A.L. 10-Step Neurodiverse Family Systems Approach Available on the UnitusTI Cloud

About the Book

Neurodiverse Family Systems: Theory and Practice offers a groundbreaking framework for understanding the unique relational dynamics that emerge within families shaped by neurological difference. Bridging developmental theory, lived neurodivergent experience, and applied clinical insight, this book challenges conventional models and introduces a nuanced approach to working with autism, ADHD, and high body empathy across generations.

Essential reading for professionals seeking to deepen their understanding of neurodiverse relational systems, it invites a rethinking of how empathy, trauma, and identity operate within the family landscape—and how meaningful change begins with neurological clarity. connection, stability, and emotional peace.

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